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Keep an eye on Intently (one)pentobarbital will lower the extent or impact of exemestane by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. For individuals receiving exemestane by using a potent CYP3A4 inducer the suggested dose of exemestane is fifty mg each day after a food.pentobarbital and olopatadine intranasa